Research Spotlight – Ana Turner, MD

A Comprehensive Guide to Long-Acting Injectable Antipsychotics for Primary Care Clinicians

Ana Turner

Ana Turner – UF Gainesville

Abi Krishna – UF Jacksonville
Shelby Goicochea – UF Jacksonville
Rishub Shah – UF Gainesville
Benton Stamper – UF Jacksonvill
Grant Harrell – UF Gainesville Primary Care

Published in: Journal of the American Board of Family Medicine

Read more: https://pubmed.ncbi.nlm.nih.gov/39455270/



What’s This Study About?

This is an overview of treatment with Long-Acting Injectable Antipsychotics (LAIs), to encourage primary care clinicians’ comfort with LAIs. These medications have been shown to decrease hospitalization rates, and increase wellbeing and quality of life of patients with severe mental illness.

Key Findings: 

We provide an overview of the treatment of severe mental illness with LAIs, focusing on the most commonly used long-acting injectable antipsychotics and the advantages and disadvantages of each, along with outlining important clinical pearls for ease of practical application. 

Why It Matters:

The article is best summarized in Figure 1, a handy flow chart describing typical treatment approaches for first identifying FDA approved uses, then key characteristics driving possible choice of Long-Acting Injectable Antipsychotics (LAIs).